Highest resolution. Quantitative phase microscope. Ever.

 CellVista SLIM

Phi Optics
Phi Optics, Inc. is an optical microscopy company that empowers bio-pharma and life sciences academia researchers to explore deeper, discover more, and ultimately cure better! Phi Optics introduces a disruptive technology – Quantitative Phase Imaging (QPI) – that provides highly accurate, fast and inexpensive imaging of live cells and tissues.

Spatial Light Interference Microscopy (SLIM)


Phi Optics SLIM quantitatively measures dry mass, height and refractive index of live samples


SLIM provides a label-free imaging method for live cells, free from phototoxicity or photobleaching


SLIM records as fast as 15 fps at full camera frame (5.5 megapixels) and displays them real-time


SLIM is compatible with most major brand microscopes and overlays with all other channels

QPI of unlabeled live cells

The microscope’s incubation system and the minimal light damage from the white-light source make Phi Optics SLIM a perfect imaging system for studying unlabeled live cells as they function and grow.

Easy Fluoresence Overlay

Phi Optics SLIM shares the same optical pathway with all the other microscopy channels. Therefore, simultaneous measurements of SLIM and fluorescence microscopy can be easily performed. The resulting images also show the exact same field of view for easy overlay

3D tomography of live cells

Phi Optics SLIM helps you look inside the cell in 3D without staining. Combined with the live cell imaging capacity, SLIM now allows for a dynamic imaging of live cells in 3D.

Automated slide scanning

Phi Optics SLIM and CellVista software perfectly integrates into your existing microscope and create an environment for automatic slide scanning. Large field-of-view scan of live samples and slide scanning of tissue biopsies are made simple and easy.

Selected publications

cell growth

M. Mir, et al., Proc. Natl. Acad. Sci., 108 (32), 13124 (2011).

tissue scanning

S. Sridharan, et al., Scientific Reports, 5, 9976 (2015)


T. Kim, et al., Nature Photonics, 8, 256-263 (2014)