Radiation Oncology testing with SLIM & GLIM at UCCI

Phi Optics recently concluded an intense demo of our quantitative phase imaging systems at the University of Cincinnati Cancer Institute in the UC College of Medicine. SLIM (Spatial Light Interference Microscopy) and GLIM (Gradient Light Interference Microscopy) were tested on irradiated samples to quantify and monitor the effects. The results were compelling, and we look forward to supporting new research coming from the institute.

Phi Optics label free quantitative phase imaging systems help to measure the effects of irradiation. In the photo above (which is actually taken from a movie) we see the effects of radiation on lymphoma spheroids in a time series. Note that the coloration is not due to tagging. Rather, it is a measurement of optical density, or signal strength (refractive index / optical path length) of light as it passes through the specimen. All colors can be adjusted. Phi Optics quantitative phase imaging instruments are excellent for long-term experiments, over days and even weeks. In addition to radiation oncology, you can use SLIM and GLIM to monitor drug delivery, cell growth and viability, assays, and more.

Here the UCCI researchers are testing GLIM monitoring on DIPG Spheroids. Sample preparation is simple, so you can spend time focusing on imaging and data collection. Contact us for more information on how our QPI instruments can help you.