Here is to a New Year of science!

As the year 2020 is drawing to a close we want to recognize your incredible strength and creativity in pushing the boundaries of science, in spite of all the challenges and difficulties.

Here is a look at some high impact journal papers that featured SLIM and GLIM this year, with a new AI method for digital staining: Phase imaging with computational specificity (PICS)!

We thank you for allowing us to support your extraordinary work and looking forward to a 2021 fueled by new science and discovery!

ER membranes exhibit phase behavior at sites of organelle contact
C. King, P. Sengupta, A. Y. Seo, J. Lippincott-Schwartz
Proceedings of the National Academy of Sciences (PNAS)
March 2020, 117 (13) 7225-7235; DOI: 10.1073/pnas.1910854117

Reproductive outcomes predicted by phase imaging with computational specificity of spermatozoon ultrastructure
M. E. Kandel, M. Rubessa, Y. R. He, S. Schreiber, S. Meyers, L. Matter Naves, M. K. Sermersheim, G. S. Sell, M. J. Szewczyk, N. Sobh, M. B. Wheeler, G. Popescu
Proceedings of the National Academy of Sciences (PNAS)
August 2020, 117 (31) 18302-18309; DOI: 10.1073/pnas.2001754117

Network science characteristics of brain-derived neuronal cultures deciphered from quantitative phase imaging data
C. Yin, X. Xiao, V. Balaban, M. E. Kandel, Y. J. Lee, G. Popescu, P. Bogdan
Nature Scientific Reports (Sci Reports)
September 2020, 10, 15078 (2020); DOI: 10.1038/s41598-020-72013-7

Electrothermal soft manipulator enabling safe transport and handling of thin cell/tissue sheets and bioelectronic devices
B. S. Kim, M. K. Kim, Y. Cho, E. E. Hamed, M. U. Gillette, H. Cha, N. Miljkovic, V. K. Aakalu, K. Kang, K.-N Son, K. M. Schachtschneider, L. B. Schook, C. Hu, G. Popescu, Y. Park, W. C. Ballance, S. Yu, S. G. Im, J. Lee, C. H. Lee, H. Kong
Science Advances (Sci Adv)
October 2020, 6 (42): EABC5630; DOI: 10.1126/sciadv.abc5630

Quantifying myelin content in brain tissue using color Spatial Light Interference Microscopy (cSLIM)
M. Fanous, M. P. Caputo, Y. J. Lee, L. A. Rund, C. Best-Popescu, M. E. Kandel, R. W. Johnson, T. Das, M. J. Kuchan, G. Popescu
Public Library of Science (PLOS) ONE
November 2020, 15(11): e0241084; DOI: 10.1073/pnas.1910854117

Integrative quantitative-phase and Airy light-sheet imaging
N. R. Subedi, P. S. Jung, E. L. Bredeweg, S. Nemati, S. E. Baker, D. N. Christodoulides, A. E. Vasdekis
Nature Scientific Reports (Sci Rep)
November 2020, 10, 20150 (2020); DOI: 10.1038/s41598-020-76730-x

Phase imaging with computational specificity (PICS) for measuring dry mass changes in sub-cellular compartments
M. E. Kandel, Y. R. He, Y. J. Lee, T. H.-Y. Chen, K. M. Sullivan, O. Aydin, M. Taher, A. Saif, H. Kong, N. Sobh, G. Popescu
Nature Communications (Nat Comm)
December 2020, 11, 6256 (2020) ; DOI: 10.1038/s41467-020-20062-x